Clinical Evidences In Wound Management

Bedsore
Orodental Care
Burn
C-Section
Nasal Irrigation
Peritonitis
Surgical Wound
DFU
Limb Ulcers
Venous Ulcers
Oxum v/s PVP-I

Treating Infected Diabetic Wounds With Superoxidised Water As An Antiseptic Agent: A Preliminary Experience

  • A significant difference was found in the favor of superoxidized water group with respect to duration of hospital stay, downgrading of the wound category and wound healing time.
  • Super-oxidized water for the management of infected diabetic wounds are encouraging.
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Superoxidized Water Improves Wound Care Outcomes In Diabetic Patients

  • A 62-year-old man without diabetes scratched his leg on a barbed wire.
  • Within 2 hours of flushing with superoxidized water & soaking in superoxidized water and wound dressing, reduction in bioburden was observed.
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Superoxidised Solution In The Management Of Lower Limb Ulcers

  • Study group included 100 patients above 18yrs of age with traumatic ulcers and diabetic ulcers.
  • Superoxidised solution is safe and effective in lower limb ulcers, with significant improvement in appearance of granulation tissue and epithelization and reduction in duration of hospital stay.
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Efficacy & Safety of Oxum in Treatment of the Venous Ulcers

  • A prospective study on using Oxum (superoxidized water) as a topical treatment for venous ulcers tested in 30 patients over 1 month.
  • The periwound erythema & periwound oedema reduction was significant from day 7.
  • On day 28, 72.3% reduction in wound size was observed.
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Evaluation of Effect and Comparison of Superoxidised Solution (Oxum) v/s Povidone Iodine (Betadine)

  • Oxum treated groups showed reduction in inflammation and early wound healing than betadine group.
  • Oxum application was safe having no pain and allergic manifestation.
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Combined Use Of Superoxidised Solution With Negative Pressure For The Treatment Of Pressure Ulcers

  • A 61-year-old patient was affected by flaccid paraplegia for 20 years because of post traumatic medullar injury level D10-D11, caused by an accidental fall, with stage IV sacral pressure ulcer for 3 years.
  • Super-oxidised was applied to control infection locally together with negative pressure to control the exudate and the local bacteremia.
  • After 6 months, a new granulation tissue formation appeared in the wound and a reduction of its diameter was observed (length 20 cm, width 15 cm, depth 5 cm).
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Bactericidal effect of electrolyzed neutral water on bacteria isolated from infected root canals

  • Electrolyzed neutral water showed a bactericidal or growth inhibitory effect against the bacteria.
  • The bactericidal effect against S. intermedia, V. parvula, P. acnes, and P. melaninogenica was observed.
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Comparative Efficacy and Tolerability of Superoxidized Solution (Oxum) against Povidone Iodine Application in Orodental Infections

  • The patients in group B (Oxum) had significantly greater reduction in pain scores compared to baseline on day 3 and day 7 than patients in group A (Povidone iodine)
  • Oxum was safe and effective for prophylaxis and treatment of orodental infections and offered better efficacy and safety response as compared to Povidone iodine application.
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Antibacterial Efficacy Of Super-Oxidized Water On Enterococcus Faecalis Biofilms In Root Canal

  • Superoxidized water has a highly antibacterial effect against E. faecalis biofilms in root canals.
  • Superoxidized water may be used as an effective irrigation solution for endodontic infection treatment.
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Evaluation Of Effect And Comparison Of Superoxidised Solution (Oxum) V/S Povidone Iodine (Betadine)

  • 90% granulation tissue formation was observed in 18 days.
  • Also, 50% reduction in hospital state was observed in Oxum group.
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Comparative Efficacy and Tolerability of Oxum against Povidone Iodine Topical Application in the Post-caesarean Section Wound Management

  • On day 5, group A (Oxum) observed granulation tissue formation as compared to group B (povidone iodine)
  • Oxum is safe and effective in post-caesarean wound care management and gives better efficacy and faster response as compared to the Povidone-iodine
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Effects of a Low Concentration Hypochlorous Acid Nasal Irrigation Solution on Bacteria, Fungi, and Virus

  • More than 99% of bactericidal or fungicidal activity was noted.
  • 3.2-log10 reduction was achieved in cells challenged with the human influenza A virus.
  • A low concentration HOCl solution can be used as an effective nasal irrigation solution.
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Comparative Evaluation of Intra-Operative Peritoneal Lavage with Super Oxidized Solution and Normal Saline in Peritonitis Cases; Randomized Controlled Trial

  • SOS significantly reduced the wound pain and infection hence resulting in early recovery.
  • Bacterial load was reduced in Group II (Oxum) as compared to Group I (Normal saline).
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Trial of Electrolyzed Strong Acid Aqueous Solution Lavage in the Treatment of Peritonitis and Intraperitoneal Abscess

  • The microorganisms had converted to a negative state within 3-7 days after the start of peritoneal lavage with electrolyzed strong acid aqueous solution twice daily.
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Outcomes Of Superoxide Solution Dressings In Surgical Wounds: A Randomized Case Control Trial.

  • The granulation tissue formation was earlier in group A (cases) as compared to group B (controls).
  • The rate of secondary infection in primary sterile wounds in group A was significantly less than in group B.
  • Super-oxide solution was found to be efficacious in different types of wounds as compared to conventional method of treatment.
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